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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c5bae107b005cbadd1f746e310e55d8684b51a2bdcf032700a9f6a7a64a6b0d' 
  AND token = '22ZCJPsAl4/6YZvTT+qLSsVFJcT+LIb2G18OzGIOxmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}