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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bae9f0a2bb2fa3192148a7002d531cf51e274aff489ea426a9fb5ed1a555a9c' 
  AND token = 'rpX5Ik5lSNtFwcfrCd3e8npm0oxz9bB9Ty5GPeDvPtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}