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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '204423ad3245e4f64cd0e4a4d2746808befad3488dc55e7469999669c8aed095' 
  AND token = 'TEmp1d/pn1lIhbbwkLcu6dIEjztROKusEgAGkfPtU34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}