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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74c37c308e713e2dd910a1273a4f572e77951d1bf1840c911d5eb9b29ec8ae42' 
  AND token = 'mO1mZRO3gHkhWt03jBq0evvRuCpjPcaw9Mm+ws5nXY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}