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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccd0e13d03830e1bc9346187bf47a9a8e0e9b4e9887547444840ecf9857c25c3' 
  AND token = 'ZUXUvGRUnbxnPBgsSkoA5n3Q2BnZcaUxKU87flSfKa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}