SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87a546a6d504015fe22a3bbc6398c1d623f8a53dca585f78b86c914b87dc5af0' 
  AND token = '3ywb39gsgZkUjfLqet2ow/8fIGomprmWesEuLgDJc7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}