SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1160d75c0322d5a226b9176aadf6845d3e7c765d7ce930bb855d568a0bf0cba9' 
  AND token = 'ntOTmrfKGiqtyhuQDAeOEpwZ7y4BPsovrWYYvS/t0Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}