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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4cf517afb6187516da746d76724156d2253c349a809555d9ac0d7a98d6c9b1' 
  AND token = 'ekW40cJhjEfN80skyxx8+eNcZDCs0eL/OoclkfnIYq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}