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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec8211e1ce528fb6fa614172489d95432abc1a9875f398b2a3d309b2766cd9d3' 
  AND token = 'xa6umw4eEgYTFfsDQ/g27d6K1Cq3/V7ptW6HeEFDdNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}