SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffdb83c73e5046117245db3831e0cc878d4f5e72f92310e15321692cba1d78f0' 
  AND token = 'wAnE+GXTLhWGGIs/A22+8aTWpfFHMpvMIzi5bdqW0qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}