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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b837468e2d79d6a02d4749853b6647ecce7576770f5d40a3a80f1a853b2ea579' 
  AND token = 'XAbBTsNVyR3qyVYf5UUN/1N2y76atcCnLiMbbxFwg78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}