SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2778b2066d4a5dc7c63f24d955734685a3c4c5e447fbf250b8fd4c35f89ac74' 
  AND token = '3SRJ8PtoKFJ29I3FPphDDFhpUSakv0vJSHgZ5eyc1uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}