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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d7dbfa10808030c9a3508b0176cf1ab7bbe03a8f2ffce622b5ca76111e64fb' 
  AND token = '20uswUwgdEIeqHF3NjHHAA/9vWozDq/zn/rcVPizSoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}