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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105a96756b3924b57e0d75804bcb1811090882b09baf038396ab2ae4b42ae9a4' 
  AND token = 'PyYlKaBSdnHTqcq5OdqnWfsq3nRNEysEI/vyUGGcYuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}