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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e30dee2daf2985834fec465a0a2519673789f0d1da985b58637acf34370f2df' 
  AND token = 'ugXYBgdTdKYTjQGp+pTAeqY0pEKJ9GvX1n0RM1yJTN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}