SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ddbe411f11dd388ee6fa3faf71e1f63ff6480703855aaf919022768199bda87' 
  AND token = 'AnX+cKj7yg/FUN6BFmLQTc0TnmP8ZreU4DU+HAxJuhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}