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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2160e443790b994a1f566be53c0493f96d7602bfbe563b85ff1b2d9812990716' 
  AND token = '9Hq7L8+v9pthJTVRMZ1z3c8kp3mA7QPgccfrgvWMUdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}