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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eec3be65ddabbabe3ace17c82d544a4d1cfe83bc6761c612654355d4381f4808' 
  AND token = 'C7OZMJPgOMPwE3+a8EDxxzOhJ4yOpOw3dDfz6xGVi/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}