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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7156bcb94de1994a87ff4e235e790aec9e6dc57658de7df68a5c955da0403ae' 
  AND token = 'zqM/8zdcYE/sEdR7ckPr5LeAhEKAI7U9kRUGzmeU8pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}