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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5224ed9235c5473aaf59f37f1c753a07267f93c8ff9cc9d29b80c911427cef91' 
  AND token = 'DaqTbAZGRV2KJTYVBifH1nQv3TvbbBjGl6mpsc5TWlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}