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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93a8c6005852f76c2d0e757d71e8060d20e5249d80c0f000f15311474421f4ad' 
  AND token = 'n2TkLXwQwmptYEn27qQgaeP0yq1bzTTY4NUl2pJkUlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}