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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e28e53e8a67ac16b58917a77b81d6aae9dc6a2dd5cac9b6a46617eed7d5a9d' 
  AND token = 'CfIXUTVANt77d4S0oXEb5OnyaKQyNaoXtmZypocpviQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}