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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e456a10b4f6e4963dcabf466f2f218ca052a30cd5c1ba174a26cd6bb48c34ef' 
  AND token = '0w5Nb1+iagiQ5tKV+3Synk2FZfwtoxu8tPBV8qV04vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}