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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f3e245c5a061201dcb05398fe82cf9b2031ec55482d3e98212d96a72d6c0d4f' 
  AND token = 'QoifDQsHkqWVxIFGFd5X65VVbkQIAOwG8YXXg1n3Cw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}