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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79e8fec081b7903f1e4c6c2ab4fb51009d89e4f3fa748a2ac250973958a8c97f' 
  AND token = 'tc9KMtR+HsFuu4p8hO5ueOey81OoLX0YItVueH2nLqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}