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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4644bfd3ad0e6b00f9fd5ecee1641580376a3d42fd7e19ce5ebad7a88e78d589' 
  AND token = 'KsFYP3+Zz1ZwINb85jjIsRp/8La6VMoEJ5uv9eFNfEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}