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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed7f765c1b02a9384e1e07abdd20a02e3f0b1271ff029d5f64186016d42c7ac' 
  AND token = 'ySmiNrkNcesuAt2zhpEYbRL15iSv8rTEymIU6A6DPn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}