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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2753127de40c09c9702002f0c82312c5cc5e80e7d357f9004570b73df1226dbe' 
  AND token = '8OOy25DB+7/MQa7kfSnXiaTUPL8jI1qtpykWRUy8BwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}