SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5284da039bebfab39324d4f7b4578cbd4a91ec2f9c9b59fdf97d31dbaec5136' 
  AND token = 'T548ob1tEXdw/WwNtRAMWBa1RPBv+RkLOtdaGPIi4AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}