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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7d2d7926310db0f193ad0a2b70a74f5b7297b04f7cbaea91a55ed3acd40ba7' 
  AND token = 'lQJOBimGig/E2Bx+dNLPN0XLnjnLtxMfdC0le+g4hS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}