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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fe1c075ac7a86dfe9f8e1d21181970de6ce75b600379e9c4fa53d6b6a8760c7' 
  AND token = '8+/LW7C/aNqcJoypmhtwJuuP6qYNMDPBJH2Tn2OLKns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}