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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c90df2df1f9c1b6de861c444e621379c57372e827d81061e984ef8ede7a8ac4' 
  AND token = 'nPxhVdxOmE41t1XAbDibUiZXaKWZkVywwuAcVQSYPkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}