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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '884466189d10b3c2dd228051d45595145ea04af5f3d5b9728e68cdb3efabbc2e' 
  AND token = 'GCJ8ZAhlSqjCcyyCw/2JQsT6865SC33PTP81U197RnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}