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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c849894793ce72d3c8974d67db9b57e29b3c741066d4f4cd93ce27be67ca2b2d' 
  AND token = 'ITYqQe/C6+nRlJ9GM/1xp2rxMOPSrVD0FJt2wLEtqCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}