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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de9b0de47c41a3b550036a7b6ec6af2e49b426793032010593172f53421e8b8' 
  AND token = 'Js2t1rcpyiofYoEexrvWt3RCjaJEwv5C9HFK0o+H7eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}