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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e85456c1b188ad6b4292a4c0b0d427d1bf5287b41eda815d380cc575ef1450ef' 
  AND token = 'n+TcC0/P0hXoGc+Z8gACZkFksrPvC1oVhJH1RMFOLiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}