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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e504b8dd2ee0883f277c61a182efbb09ac09997228fba10595ca65290efb2cf' 
  AND token = '9q/L0hYF6F1Sk5zs5IYnaNlJFh7Z7G9XuuXik9kT4OU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}