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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e31867aecfe1b67005f848cb71d98fbd42441f822792b5ebf0c4cc4d7cc1b3b2' 
  AND token = 'AbInQkpo8I5mIolHdPYMH4kSRYe/iam5LXKkA6rb6E8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}