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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dcce3771bd258db1b32566a57be071da43271e126387be3c5731e40c7c843b2' 
  AND token = 'lrm9p09m/YnkpDdGNxDBnehem0UHlA8IF0tmZcwxZwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}