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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16fc1e540448471143a8aa37be715d077548a4f6853abe84bcf8390903122b7a' 
  AND token = 'PM+oFG2rRDUw89Ea1eVwyb5whjvOiqrXXZVB0qt1xmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}