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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aeb218e24f30269a8e32bdc9bd48c405ed56eb990222729afb5d3162781700d' 
  AND token = '4IkTZL0hE69LlKl4MCVH5Gjn6ReSrnEsu+7DAx2FHj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}