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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db44c49b1e60cbd8251ab0c39482c1637b23d3e3c59d8e9b09666fb82c83696' 
  AND token = 'IvyVDSyGJBInL4DL0V66JpUK75aGqqy2zGxSBYjcFSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}