SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d1bef435a49aa11eceb6de5ca1ebadb19f3a749d450ee4eca120fdbb172312' 
  AND token = '9IlgDAnrhE4SAerffioRNpe08quRAkpDgti3L0XEbx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}