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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e97f21b95992d408481967ed679c2432a5cd805ab03f59ebb9c1e0180b992f0b' 
  AND token = '2Fmr734SjlklxarrxFZR0NHsIzBvL1X0F/5Tatyq1vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}