SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5ada111af8b33535ea164da19f4fe6fd32ac1d74b7c3b29726223c71c4df44d' 
  AND token = '4Q0S5M4xZ5vfDClCWy+POdefZN9cxMhk7fDhgukXJms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}