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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b3c30cda44a82b0e563261a51887ac8e31843af4cdfb926f90f130b618f977' 
  AND token = 'eHkR5PxYncY4Fw/10f6hq4O+Fb9woUMsaJYNDyJ6Yd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}