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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ff1fc20116b36fdbc4bd66b220d78008d8f19cbc3316b5a666398e2088885a7' 
  AND token = '961cqWxttXkplrgABj7zNhDyXDgA0S8v2tEfT+e0yMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}