SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4c62620e78ba222a8f5ad37ff16125e56ec70efaeadb4f86a6aebb9e9f03c64' 
  AND token = 'X/avCduP8OISWg7qwDmJM/EX/TSeO3VGgOJiIkxzgQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}