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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a2b5a308fe12e3eedd9f1a7ae5953e3f7faabb74999603a544c329fb430f7bd' 
  AND token = 'R7l4Jy3XXkAGgB/NAiiPYRR+dMw29FiiYjOs1PnNn3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}