SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88847386d8409cb363e7a458cb831cf35ef4aa85291b93f6308ab1c7b2053ee8' 
  AND token = 'QVMPX6Llkfc6k3DYyyZe9r3iXmSbuxwi81b4m6t6MjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}